The second interregional learning event of the STEPHANIE project took place in Prague on 7th-8th June 2017. Day 1 of the meeting was attended by representatives from partner regions (partners and invited stakeholders) and by a number of stakeholders from the local R&D community. It was designed to share experiences and insights on the role of quadruple helix in directing R&I policies towards marketable and society orientated products and services. Content included input presentations, study visits and participatory discussion sessions. Day 2 was open to partners and continued debate on project content initiated in Day 1. In particular, partners discussed the next activities to be carried out in order to gather Good Practices from the regional SPIA meetings. The second Steering Group meeting took place, with a particular focus on Communication Activities, on the next Milestones and the preparation oft he third Interregional Learning Event.